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Table 1 Summary of baseline demographic and clinical features of patients stratified by group.

From: Clinical characteristics and outcomes of patients with acute myelogenous leukemia admitted to intensive care: a case-control study

Variable

Total

(n = 320)

AML ICU Cases

(n = 45)

AML non-ICU Controls

(n = 50)

Non-AML ICU Controls

(n = 225)

p-value

Age (mean [SD]) (years)

54.6 (13.7)

54.8 (13.1)

53.4 (16.2)

54.8 (13.2)

0.75

Female sex (%)

91 (28.4)

13 (28.9)

11 (22.0)

67 (29.8)

0.56

BMI (mean [SD]) (kg/m 2 )

29.3 (7.1)

30.7 (6.6)

29.8 (6.4)

27.0 (7.9)

0.13

Co-morbid disease type (%)

     

   Leukemia

102 (31.9)

45 (100)

50 (100)

7 (3.1)

< 0.001

   Lymphoma

5 (1.6)

2 (2.2)

0 (0)

4 (1.8)

0.81

   Solid organ tumor

8 (2.5)

1 (2.2)

0 (0)

7 (3.1)

0.64

   Congestive heart failure

11 (3.4)

1 (2.2)

3 (6.0)

7 (3.1)

0.62

   Chronic lung Disease

16 (5.0)

0 (0)

3 (6.0)

13 (5.8)

0.28

   Chronic kidney disease

19 (5.9)

0 (0)

2 (4.0)

17 (7.6)

0.13

   Liver disease

41 (12.8)

1 (2.2)

2 (4.0)

38 (16.9)

0.002

   HIV/AIDS

5 (1.6)

0 (0)

1 (2.0)

4 (1.8)

1.0

Co-morbid disease (%) ¶

     

   None (%)

143 (44.7)

24 (53.3)

0 (0)

119 (52.9)

< 0.001

   1

149 (46.6)

19 (42.2)

41 (82.0)

89 (39.6)

 

   2

26 (8.1)

2 (4.4)

7 (14.0)

17 (7.6)

 

   ≥3

2 (0.6)

0 (0)

2 (4.0)

0 (0)

 

Surgical admission (%)

54 (16.9)

1 (2.2)

0 (0)

53 (23.6)

< 0.001

  1. Abbreviations: BMI = body mass index; HIV = human immunodeficiency virus; AIDS = acquired immunodeficiency syndrome
  2. § Included prior myocardial infarction, congestive heart failure, and/or peripheral vascular disease
  3. ¶ Co-morbid disease excluding AML diagnosis