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Table 1 Summary of baseline demographic and clinical features of patients stratified by group.

From: Clinical characteristics and outcomes of patients with acute myelogenous leukemia admitted to intensive care: a case-control study

Variable Total
(n = 320)
AML ICU Cases
(n = 45)
AML non-ICU Controls
(n = 50)
Non-AML ICU Controls
(n = 225)
p-value
Age (mean [SD]) (years) 54.6 (13.7) 54.8 (13.1) 53.4 (16.2) 54.8 (13.2) 0.75
Female sex (%) 91 (28.4) 13 (28.9) 11 (22.0) 67 (29.8) 0.56
BMI (mean [SD]) (kg/m 2 ) 29.3 (7.1) 30.7 (6.6) 29.8 (6.4) 27.0 (7.9) 0.13
Co-morbid disease type (%)      
   Leukemia 102 (31.9) 45 (100) 50 (100) 7 (3.1) < 0.001
   Lymphoma 5 (1.6) 2 (2.2) 0 (0) 4 (1.8) 0.81
   Solid organ tumor 8 (2.5) 1 (2.2) 0 (0) 7 (3.1) 0.64
   Congestive heart failure 11 (3.4) 1 (2.2) 3 (6.0) 7 (3.1) 0.62
   Chronic lung Disease 16 (5.0) 0 (0) 3 (6.0) 13 (5.8) 0.28
   Chronic kidney disease 19 (5.9) 0 (0) 2 (4.0) 17 (7.6) 0.13
   Liver disease 41 (12.8) 1 (2.2) 2 (4.0) 38 (16.9) 0.002
   HIV/AIDS 5 (1.6) 0 (0) 1 (2.0) 4 (1.8) 1.0
Co-morbid disease (%)      
   None (%) 143 (44.7) 24 (53.3) 0 (0) 119 (52.9) < 0.001
   1 149 (46.6) 19 (42.2) 41 (82.0) 89 (39.6)  
   2 26 (8.1) 2 (4.4) 7 (14.0) 17 (7.6)  
   ≥3 2 (0.6) 0 (0) 2 (4.0) 0 (0)  
Surgical admission (%) 54 (16.9) 1 (2.2) 0 (0) 53 (23.6) < 0.001
  1. Abbreviations: BMI = body mass index; HIV = human immunodeficiency virus; AIDS = acquired immunodeficiency syndrome
  2. § Included prior myocardial infarction, congestive heart failure, and/or peripheral vascular disease
  3. ¶ Co-morbid disease excluding AML diagnosis