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Table 3 Hyaluronan staining in human endometrium and its lesions

From: Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma

 

HA-staining

intensity

 

HA-staining

intensity

 
 

Epithelium*

  

Stroma*

  
 

n.d.

weak

moderate

strong

n.d.

weak

moderate

strong

Normal n = 9

9

0

0

0

0

0

9 (60%; 10-90%)

0

Proliferating pm n = 5

5

0

0

0

0

3

1 (30%)

1 (100%)

Hyperplasia # n = 2

0

1 (5%)

1 (40%)

0

0

1 (40%)

0

1 (30%)

Grade 1 n = 8

1

0

5 (2-5%)

2 (5-10%)

0

0

5 (70%; 20-80%)

3 (80%; 50-100%)

Grade 2+3 n = 8

1

0

4 (15%; 10-60%)

3 (30%; 20-30%)

0

0

2 (50-80%)

6 (80%; 20-90%)

  1. * num. of samples with % of positive cells (% in median; range when necessary)
  2. n.d. = not detected/negative
  3. # complex atypical hyperplasia
  4. pm = post-menopausal
  5. ‡ endometrioid endometrial adenocarcinoma