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Table 2 Response according to CYP1B1 polymorphisms

From: Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients

  CR+PR (N = 29) SD+PD (N = 31)  
Genotype N (%) N (%) P
CYP1B1 4326CG    
   CC + GC 23 (62.2) 14 (37.8) 0.014
   GG 6 (26.1) 17 (73.9)  
CYP1B1 4390GA    
   AA 21 (56.8) 16 (43.2) 0.164
   AG+ GG 8 (34.8) 15 (65.2)  
CYP1B1 412CG    
   CC + CG 14 (48.3) 15 (51.7) 0.993
   GG 15 (48.4) 16 (51.6)  
  1. Abbreviations: CR complete response; PD, progressive disease; PR, partial response; SD, stable disease. P was calculated with Pearson-χ2 two-sided test with continuity correction