Skip to main content

Table 2 Response according to CYP1B1 polymorphisms

From: Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients

 

CR+PR (N = 29)

SD+PD (N = 31)

 

Genotype

N (%)

N (%)

P

CYP1B1 4326CG

   

   CC + GC

23 (62.2)

14 (37.8)

0.014

   GG

6 (26.1)

17 (73.9)

 

CYP1B1 4390GA

   

   AA

21 (56.8)

16 (43.2)

0.164

   AG+ GG

8 (34.8)

15 (65.2)

 

CYP1B1 412CG

   

   CC + CG

14 (48.3)

15 (51.7)

0.993

   GG

15 (48.4)

16 (51.6)

 
  1. Abbreviations: CR complete response; PD, progressive disease; PR, partial response; SD, stable disease. P was calculated with Pearson-χ2 two-sided test with continuity correction
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us