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Table 5 Predictive factors of overall survival in univariate and multivariate analysis

From: Esophageal cancer in the elderly: an analysis of the factors associated with treatment decisions and outcomes

 

Univariate analysis Median overall survival

Multivariate analysis HR [95% CI]

Age ≥ 75 years

ns

 

Sex

ns

 

WHO performance status < 2

  

   no

4.2 ± 0.2 *

1 [reference]

   yes

17.8 ± 1.5

2.3 [1.6-3.4] *

Initial weight loss < 10%

  

   yes

6.3 ± 0.4 *

1 [reference]

   no

17.5 ± 0.9

1.6 [1.1-2.3] *

Charlson score ≤ 1

ns

 

Histology

ns

 

Tumor stage

  

   IV

4.2 ± 0.2

1 [reference]

   III

10.7 ± 2.3

1.7 [1.1-2.6] *

   II

15.2 ± 2.8

1.6 [1.1-2.5] *

   I

67.7 ± 7.0 *

4.5 [1.9-11.1] *

Treatment

  

   BSC

3.4 ± 0.3 *

1 [reference]

   carcinologic treatment

14.3 ± 3.3

4.4 [2.4-8.1] *

  1. HR: Hazard ratio, CI: confidence interval, BSC: best supportive care, *: p < 0.05, ns: not significant