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Table 5 Predictive factors of overall survival in univariate and multivariate analysis

From: Esophageal cancer in the elderly: an analysis of the factors associated with treatment decisions and outcomes

  Univariate analysis Median overall survival Multivariate analysis HR [95% CI]
Age ≥ 75 years ns  
Sex ns  
WHO performance status < 2   
   no 4.2 ± 0.2 * 1 [reference]
   yes 17.8 ± 1.5 2.3 [1.6-3.4] *
Initial weight loss < 10%   
   yes 6.3 ± 0.4 * 1 [reference]
   no 17.5 ± 0.9 1.6 [1.1-2.3] *
Charlson score ≤ 1 ns  
Histology ns  
Tumor stage   
   IV 4.2 ± 0.2 1 [reference]
   III 10.7 ± 2.3 1.7 [1.1-2.6] *
   II 15.2 ± 2.8 1.6 [1.1-2.5] *
   I 67.7 ± 7.0 * 4.5 [1.9-11.1] *
Treatment   
   BSC 3.4 ± 0.3 * 1 [reference]
   carcinologic treatment 14.3 ± 3.3 4.4 [2.4-8.1] *
  1. HR: Hazard ratio, CI: confidence interval, BSC: best supportive care, *: p < 0.05, ns: not significant