Predictive factors of radiation-induced skin toxicity in breast cancer patients

BMC Cancer

Table 1 Clinical and treatment characteristics of patients

	Total	MRM	BCS	P value
Patients (No)	158	90	68
Age
Mean±SD (y/o)	50 ± 11	56 ± 11	48 ± 10
Range	24-86	26-86	24-78
Acute skin toxicity
Grade 2	34	23	11	0.27
Grade 3	3	1	2
CTV
Volume (c.c)	192 ± 59	169 ± 53	226 ± 63
D _mean (Gy)	53.2	53.1	53.3
D _median (Gy)	53.9	54.5	53.5
V_100% (%)	98	98	99
PTV
Volume (c.c)	413 ± 113	345 ± 102	504 ± 124
D _mean (Gy)	52.5	52.5	52.5
D _median (Gy)	53.1	53.0	53.0
V_100% (%)	94	93	95
PTV-V ₁₀₇ (Median; cc)	101	81	132
PTV-V _107%,
Median (%)	28.6	24.5	31.5
>Median (28.6) (No)	79	40	39
< = Median (No)	79	50	29	0.11
TV-V ₁₁₀ (Median; cc)	35	32	36
TV-V _110%
Median (%)	5.13	5.59	4.37
>Median (5.13) (No)	79	48	31
< = Median (No)	79	42	37	0.33

Abbreviation: MRM= modified radical mastectomy, BCS= breast-conserving surgery D_mean = mean received dose for target; D_median = median received dose for target
V_100% = percent volume receiving the prescribed dose
PTV-V_107% = percent volume receiving 107% of prescribed dose within PTV
Treated volume (TV) = the tissue volume which received the prescribed dose
TV-V_110% = percent volume receiving 110% of prescribed dose within TV
Data are presented as mean with standard deviation

ISSN: 1471-2407