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Figure 5 | BMC Cancer

Figure 5

From: Co-expression of nuclear and cytoplasmic HMGB1 is inversely associated with infiltration of CD45RO+ T cells and prognosis in patients with stage IIIB colon cancer

Figure 5

Double staining of HMGB1 and CD45RO+ cells in stage IIIB colon cancer (red staining of HMGB1 in cancer cells and brown staining of CD45RO+ cells in the stroma). Strong nuclear staining of HMGB1 was associated with a high density of CD45RO+ cells infiltrating into colon cancer tissues (×100 in A and ×400 in B, "↑"refers to nuclear staining in cancer cells). Strong nuclear and cytoplasmic staining of HMGB1 was also associated with a low density of CD45RO+ cells infiltrating into colon cancer tissues (×100 in C and ×400 in D, "↑"refers to nuclear or cytoplasmic staining in cancer cells).

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