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Table 3 Correlation between SPHK1 expression and clinicopathologic characteristics of SGC

From: Overexpression of sphingosine kinase 1 is associated with salivary gland carcinoma progression and might be a novel predictive marker for adjuvant therapy

Characteristics

SPHK1

Chi-square test P-value

  

Low or none No. cases (%)

High No. cases (%)

 

Gender

Male

45 (67.2)

44 (47.8)

0.150

 

Female

22 (32.8)

48 (52.2)

 

Age (years)

≥ 47

34 (50.7)

47 (51.1)

0.966

 

< 47

33 (49.3)

45 (48.9)

 

Clinical Stage

I

10 (13.5)

6 (7.1)

0.005

 

II

35 (47.3)

23 (27.1)

 
 

III

16 (21.6)

23 (27.1)

 
 

IV

13 (17.6)

33 (38.8)

 

T classification

T1

10 (13.5)

7 (8.2)

0.017

 

T2

40 (54.1)

32 (37.6)

 
 

T3

16 (21.6)

21 (24.7)

 
 

T4

8 (10.8)

25 (29.4)

 

N classification

N0

60 (81.1)

58 (68.2)

0.009

 

N1

9 (12.2)

12 (14.1)

 
 

N2

5 (6.8)

15 (17.6)

 
 

N3

0 (0.0)

0 (0.0)

 

M classification

No

61 (80.6)

52 (64.1)

0.002

 

Yes

13 (19.4)

33 (35.9)

 

Pathologic Differentiation

Poor

57(35.8)

44(27.7)

0.013

 

Moderate

4(2.5)

0(0.0)

 
 

Well

24(15.1)

30(18.9)

 

Histological Types

MEC

15(20.3)

22(25.9)

0.945

 

ACC

11(14.9)

12(14.1)

 
 

AcCC

9(12.2)

9(10.6)

 
 

SDC

9(12.2)

9(10.6)

 
 

Other histological types

30(40.5)

33(38.8)

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