Figure 4From: Thrombospondin-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylation THBS4 methylation is significantly higher in neoplastic tissue compared to adjacent normal tissue. THBS4 methylation was significantly higher in neoplastic tissues compared to the adjacent normal tissue (p < 0.0001). The median PMR in normal mucosa was 0.06 compared with a PMR of 2.6 in tumour tissue.Back to article page