From: Gross genomic alterations and gene expression profiles of high- grade serous carcinoma of the ovary with and without BRCA1 inactivation
BRCA1 status
S-phase
Low (%)
High (%)
Total (%)
p value
BRCA1 loss through mutation
6 (75)
2 (25)
8 (28.6)
BRCA1 epigenetic loss
3 (33.3)
6 (66.7)
9 (32.1)
No BRCA1 loss
5 (45.5)
6 (54.5)
11 (39.3)
0.1