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Table 1 BRCA1 status in diploid, aneuploid and tetraploid tumors.

From: Gross genomic alterations and gene expression profiles of high- grade serous carcinoma of the ovary with and without BRCA1 inactivation

BRCA1 status

DNA ploidy diagnosis

 

Diploid(%)

Aneuploid(%)

Tetraploid(%)

Total(%)

p value

BRCA1 loss through mutation

2 (25)

3 (37.5)

3 (37.5)

8 (28.6)

 

BRCA1 epigenetic loss

3 (33.3)

4 (44.4)

2 (22.2)

9 (32.1)

 

No BRCA1 loss

4 (36.4)

5 (45.5)

2 (18.2)

11(39.3)

0.96

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BMC Cancer

ISSN: 1471-2407

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