Table 1 Genes displaying differential expression between HB4a and C3.6 cell lines.

*ALDH1A3

ENSG00000184254:ALDEHYDE DEHYDROGENASE 6

GO:0006629:lipid metabolism

5.45

KRT15

ENSG00000171346:KERATIN, TYPE I CYTOSKELETAL 15

GO:0008544:epidermal differentiation

4.66

*AGR2

ENSG00000106541:ANTERIOR GRADIENT 2

Unknown

4.00

NCKAP1

ENSG00000061676:NCK-ASSOCIATED PROTEIN 1 (NAP 1)

GO:0006915:apoptosis

3.87

COX6C

ENSG00000164919:CYTOCHROME C OXIDASE POLYPEPTIDE VIC

GO:0006091:energy pathways

3.37

PSCA

ENSG00000167653:PROSTATE STEM CELL ANTIGEN PRECURSOR

Unknown

2.94

*KRT13

ENSG00000171401:KERATIN, TYPE I CYTOSKELETAL 13

GO:0008544:epidermal differentiation

2.69

YWHAZ

ENSG00000164924:14-3-3 PROTEIN ZETA/DELTA

GO:0007165:signal transduction

2.47

*S100P

ENSG00000163993:S-100P PROTEIN

Unknown

2.45

*PKM2

ENSG00000067225:PYRUVATE KINASE, MUSCLE

GO:0006096:glycolysis

2.41

TRAM1

ENSG00000067167:TRAM PROTEIN

GO:0006605:protein targeting

2.38

ATP5L

ENSG00000167283:ATP SYNTHASE G CHAIN, MITOCHONDRIAL

GO:0015992:proton transport; GO:0006754:ATP biosynthesis

2.26

SLC7A7

ENSG00000155465:Y+L AMINO ACID TRANSPORTER 1

GO:0006832:small molecule transport

2.25

SSBP1

ENSG00000106028:SINGLE-STRANDED DNA-BINDING PROTEIN

GO:0006260:DNA replication

2.25

SERF2

ENSG00000140264:SMALL EDRK-RICH FACTOR 2

Unknown

2.21

NEDD9

ENSG00000111859:ENHANCER OF FILAMENTATION 1 (HEF1)

GO:0007155:cell adhesion; GO:0000074:regulation of cell cycle

2.18

SCAMP2

ENSG00000140497:SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 2

GO:0006886:intracellular protein transport

2.12

EMP1

ENSG00000134531:EPITHELIAL MEMBRANE PROTEIN-1

GO:0007048:oncogenesis;GO:0008283:cell proliferation

2.10

*LCP1

ENSG00000136167:L-PLASTIN

Unknown

2.09

MGST1

ENSG00000008394:MICROSOMAL GLUTATHIONE S-TRANSFERASE 1

GO:0032496: response to lipopolysaccharide

2.06

DUT

ENSG00000128951:DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE

GO:0006260:DNA replication

2.05

DDX5

ENSG00000108654:PROBABLE RNA-DEPENDENT HELICASE P68

GO:0016049:cell growth

2.00

SRP14

ENSG00000140319:SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN

GO:0006605:protein targeting

1.98

*ANXA2

ENSG00000183059:ANNEXIN II (LIPOCORTIN II)

GO:0001501:skeletal development

1.95

PBP

ENSG00000089220:PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN

Unknown

1.80

ATP5G3

ENSG00000154518:ATP SYNTHASE LIPID-BINDING PROTEIN

GO:0006091:energy pathways; GO:0015992:proton transport

1.78

SRI

ENSG00000075142:SORCIN (22 KDA PROTEIN)

GO:0007517:muscle development

1.77

RPL17

ENSG00000141618:60S RIBOSOMAL PROTEIN L17

GO:0006412:protein biosynthesis

1.71

*ERBB2

ENSG00000141736:V-ERBB2 ERYTHROBLASTIC LEUKEMIA VIRAL ONCOGENE HOMOLOG 2

GO:0007169:transmembrane receptor protein tyrosine kinase signaling

1.67

*AKR1B1

ENSG00000085662:ALDOSE REDUCTASE

GO:0005975:carbohydrate metabolism

1.66

ATP6V1F

ENSG00000128524:VACUOLAR ATP SYNTHASE SUBUNIT F

GO:0015992:proton transport; GO:0006754:ATP biosynthesis

1.66

ATP5G1

ENSG00000159199:ATP SYNTHASE LIPID-BINDING PROTEIN

GO:0015992:proton transport

1.64

UBN1

ENSG00000118900:UBINUCLEIN 1

GO:0016568:chromatin modification

1.63

*ERBB3

ENSG00000065361:V-ERBB2 ERYTHROBLASTIC LEUKEMIA VIRAL ONCOGENE HOMOLOG 3

GO:0007169:transmembrane receptor protein tyrosine kinase signaling

1.62

FTH1

ENSG00000167996:FERRITIN HEAVY CHAIN

GO:0008283:cell proliferation; GO:0006826:iron transport

1.62

ST14

ENSG00000149418:SUPPRESSOR OF TUMORIGENICITY 14

GO:0006508:proteolysis and peptidolysis

1.62

*PHB

ENSG00000167085:PROHIBITIN

GO:0008151:cell growth and/or maintenance

1.59

CLTC

ENSG00000141367:CLATHRIN HEAVY CHAIN 1

GO:0006886:intracellular protein transport

1.51

APLP2

ENSG00000084234:AMYLOID-LIKE PROTEIN 2 PRECURSOR

GO:0007186:G-protein coupled receptor protein signaling pathway

1.48

HSBP1

ENSG00000166530:HEAT SHOCK FACTOR BINDING PROTEIN 1

GO:0000122:negative regulation of transcription from Pol II promoter

1.48

*NME1

ENSG00000239672:NON-METASTATIC CELLS 1

GO:0045786:negative regulation of cell cycle; GO:0009142: NTP biosynthesis

1.47

*CPNE3

ENSG00000085719:COPINE III

Unknown

1.46

*ISGF3G †

ENSG00000213928:INTEREFERON REGULATORY FACTOR 9

GO:0006355:regulation of transcription; GO:0006955: immune response

0.73

*USP14 †

ENSG00000101557:UBIQUITIN SPECIFIC PEPTIDASE 14

GO:0006511:ubiquitin-dependent protein catabolism

0.71

SSR4

ENSG00000180879:SIGNAL SEQUENCE RECEPTOR DELTA

GO:0006886:intracellular protein transport

0.69

RAB7

ENSG00000075785:RAS-RELATED PROTEIN RAB-7

GO:0007264:small GTPase mediated signal transduction; GO:0006897:endocytosis

0.69

SHMT2

ENSG00000182199:SERINE HYDROXYMETHYLTRANSFERASE

GO:0006520:amino acid metabolism

0.68

NGFRAP1

ENSG00000166681:NERVE GROWTH FACTOR RECEPTOR ASSOCIATED PROTEIN 1

GO:0007275:development; GO:0006915:apoptosis

0.66

HAT1

ENSG00000128708:HISTONE ACETYLTRANSFERASE 1

GO:0006323:DNA packaging; GO:0006475: internal protein amino acid acetylation

0.65

PPP1CA

ENSG00000172531:SERINE/THREONINE PROTEIN PHOSPHATASE PP1-ALPHA 1 CATALYTIC SUBUNIT

GO:0006470:protein amino acid dephosphorylation

0.65

UBL1

ENSG00000116030:UBIQUITIN-LIKE PROTEIN SMT3C PRECURSOR

GO:0006281:DNA repair

0.65

NPC2

ENSG00000119655:EPIDIDYMAL SECRETORY PROTEIN E1 PRECURSOR

GO:0000004:biological_process unknown

0.65

GMPS

ENSG00000163655:GMP SYNTHASE

GO:0006164:purine nucleotide biosynthesis

0.62

UBE2L6 †

ENSG00000156587:UBIQUITIN-CONJUGATING ENZYME E2L 6

GO:0006512:ubiquitin cycle

0.61

SF3B1

NSG00000115524:SPLICING FACTOR 3B SUBUNIT 1

GO:0006371:mRNA splicing

0.58

ANXA1

ENSG00000135046:ANNEXIN I

GO:0006928:cell motility;GO:0006629:lipid metabolism

0.57

SDC1

ENSG00000115884:SYNDICAN 1

GO:0048627:myoblast development

0.56

FXR1

ENSG00000114416:FRAGILE X MENTAL RETARDATION SYNDROME RELATED PROTEIN 1

GO:0006915:apoptosis

0.56

PLD3

ENSG00000105223:SIMILAR TO VACCINIA VIRUS HINDIII K4L ORF

GO:0008152:metabolism

0.53

RPN1

ENSG00000163902:DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE

GO:0006464:protein modification

0.51

*GSTP1 †

ENSG00000084207:GLUTATHIONE S-TRANSFERASE P

GO:0007417:central nervous system development

0.51

HDLBP

ENSG00000115677:VIGILIN (HIGH DENSITY LIPOPROTEIN-BINDING PROTEIN)

GO:0006869:lipid transport; GO:0008203:cholesterol metabolism

0.5

TYMS

ENSG00000176890:THYMIDYLATE SYNTHASE

GO:0006139:nucleobase, nucleoside, nucleotide and nucleic acid metabolism

0.44

WFDC2

ENSG00000101443:MAJOR EPIDIDYMIS-SPECIFIC PROTEIN E4 PRECURSOR

GO:0006508:proteolysis and peptidolysis

0.43

OAS1 †

ENSG00000089127:2',5'-OLIGOADENYLATE SYNTHETASE 1

GO:0006955:immune response

0.42

SERPINH1

ENSG00000149257:COLLAGEN-BINDING PROTEIN 2 PRECURSOR

GO:0006950:response to stress

0.39

CYBA

ENSG00000051523:CYTOCHROME B-245 ALPHA

GO:0006118:electron transport; GO:0006801: superoxide metabolism

0.38

IFITM2 †

ENSG00000185201:INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 2

GO:0006955:immune response

0.34

IGFBP3

ENSG00000146674:INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 PRECURSOR

GO:0007165:signal transduction; GO:0001558:regulation of cell growth

0.31

ALDH1A1

ENSG00000165092:ALDEHYDE DEHYDROGENASE 1 FAMILY MEMBER A1

GO:0006081:aldehyde metabolism

0.29

IFITM1 †

ENSG00000185885:INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 1

GO:0006955:immune response; GO:0008285:negative regulation of cell proliferation

0.25

*G1P2 †

ENSG00000182106:UBIQUITIN CROSS-REACTIVE PRECURSOR

GO:0006955:immune response; GO:0007267:cell-cell signaling

0.17