Table 3 Incidence rate ratios (IRR) for colorectal cancer per additional intake of 25 g red or processed meat subdivided by the studied genotypes.
From: Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes
Red and processed meat | |||||||
|---|---|---|---|---|---|---|---|
Ncases | Nsub-cohort | IRRA | 95% CI | IRRB | 95% CI | p-valueC | |
NFkB -94ins/del | |||||||
II | 121 | 307 | 0.96 | (0.90-1.03) | 0.97 | (0.90-1.04) | 0.03 |
ID and DD | 257 | 449 | 1.03 | (0.98-1.08) | 1.03 | (0.98-1.09) | |
PXR rs1523127 | |||||||
AA | 127 | 257 | 1.04 | (0.98-1.12) | 1.04 | (0.97-1.12) | 0.28 |
AC and CC | 251 | 499 | 1.01 | (0.96-1.06) | 1.01 | (0.96-1.07) | |
PXR rs2276707 | |||||||
CC | 237 | 441 | 1.02 | (0.97-1.08) | 1.02 | (0.97-1.08) | 0.53 |
CT and TT | 141 | 315 | 1.01 | (0.95-1.07) | 1.01 | (0.94-1.08) | |
PXR rs6785049 | |||||||
AA | 136 | 259 | 1.01 | (0.95-1.07) | 1.01 | (0.95-1.08) | 0.72 |
AG and GG | 242 | 497 | 1.02 | (0.97-1.08) | 1.02 | (0.97-1.08) | |
LXR rs1405655 | |||||||
CC | 169 | 347 | 1.02 | (0.97-1.07) | 1.02 | (0.96-1.08) | 0.91 |
CT and TT | 209 | 409 | 1.02 | (0.96-1.08) | 1.02 | (0.96-1.08) | |
LXR rs2695121 | |||||||
TT | 117 | 221 | 1.04 | (0.98-1.12) | 1.05 | (0.97-1.12) | 0.28 |
CT and CC | 261 | 535 | 1.01 | (0.96-1.07) | 1.01 | (0.96-1.07) | |