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Figure 9 | BMC Cancer

Figure 9

From: 17-Allylamino-17-demethoxygeldanamycin induces downregulation of critical Hsp90 protein clients and results in cell cycle arrest and apoptosis of human urinary bladder cancer cells

Figure 9

17-AAG induces downregulation of FOXO and ERK1/2 signaling mediators in bladder cancer cells. Detection of total and constitutively phosphorylated protein levels of FOXO transcription factors and Erk1/2 (p44/42) kinases in all three bladder cancer cell lines, upon 17-AAG administration for 24 hours, via a Western blotting approach. All immunoblotting experiments were repeated three times.

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BMC Cancer

ISSN: 1471-2407

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