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Table 3 Comparison between histopathological or molecular parameters and response to therapy

From: Molecular alterations in key-regulator genes among patients with T4 breast carcinoma

A                
Outcome ER PR Ki67 HER2    
  positives % P positives % P positives % P positives % P    
Clinical response    0.132    0.640    0.047    0.022    
   Complete response 3/7 43   3/7 43   5/7 71   8/8 100     
Partial response 16/29 55   11/29 38   9/27 33   27/37 73     
< Partial response 5/8 62   2/8 25   2/8 25   2/8 25     
Pathological response    0.469    0.235    0.042    0.095    
pCR 4/7 57   3/7 43   5/7 71   7/8 87     
<pCR 20/37 54   13/37 35   11/35 31   30/45 67     
B                
Outcome cyclinD1 h-prune pERK 1-2 p53 survivin
  positives % P positives % P positives % P positives % P    
Clinical response    0.457    0.824    0.032    0.391    0.089
   Complete response 1/8 12   1/8 12   0/8 0   1/8 12   1/8 12  
Partial response 8/37 22   5/37 14   3/37 8   10/37 27   15/37 41  
< Partial response 3/8 37   2/8 25   2/8 25   2/8 25   5/8 62  
Pathological response    0.660    0.822    0.007    0.972    0.234
pCR 2/8 25   1/8 12   0/8 0   2/8 25   3/8 37  
<pCR 10/45 22   7/45 16   5/45 11   11/45 24   18/45 40  
  1. pCR, pathological complete response