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Figure 8 | BMC Cancer

Figure 8

From: Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers

Figure 8

Genes in overlapping recurrent CNAs of human and mouse breast tumor determined by cross species comparative-KC-SMART analyses. Overview of genes in regions found by cross species comparative-KC-SMART analysis (Figure 7). Listed are genes that map to significantly differentially gains and losses that overlap (a) between mouse Brca1 Δ/Δ ;p53 Δ/Δmammary tumors (compared to p53 Δ/Δtumors) and human BRCA1-mutated breast tumors (compared to control tumors) and (b) between mouse Brca2Δ/Δ;p53Δ/Δ mammary tumors (compared to p53Δ/Δ tumors) and BRCA2-mutated breast tumors (compared to control tumors). Idem Figure 6. For complete list see Additional file 9.

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