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Table 4 Functional classification of 40 differentially expressed genes in CD133+ vs.CD133- GBM samples

From: Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas

CATEGORY

P-VALUE

MOLECULES

Protein Synthesis

1,14E-10-1,14E-10

EIF2AK4, RPL22, RPS4X, RPS3A, RPL27A, RPL7A, RPL39, RPL23A, RPL41, RPL7

Cancer

1,17E-04-4,38E-02

HUWE1, TRA2B, VIM, PLK1, TUBA1B, ACTG1, RPL7, TPT1, RPS4X, RPS3A, H3F3A, RPS16, GLUL, HSP90AA1, CLEC2D

Cellular Growth and Proliferation

1,94E-03-2,89E-02

HUWE1, PLK1, RPL23A

Cell Death

1,99E-03-3,52E-02

HUWE1, RPS3A, HSP90AA1, VIM, PLK1

Cell Morphology

1,99E-03-2,36E-02

VIM

Cellular Assembly and Organization

1,99E-03-3,71E-02

VIM, PLK1, ACTG1, RPL7

DNA Replication, Recombination, and Repair

1,99E-03-3,71E-02

HUWE1, VIM, PLK1

Cell-To-Cell Signalling and Interaction

3,97E-03-9,9E-03

VIM

Cellular Function and Maintenance

5,49E-03-2,94E-02

EIF2AK4, HSP90AA1, VIM, ACTG1

Cellular Development

5,95E-03-1,97E-02

EIF2AK4, HSP90AA1, VIM

Neurological Disease

9,02E-03-4,28E-02

TPT1, RPS4X, RPS3A, RPL39, VIM, ACTG1, NSMAF, TUBA1B, CALM2

Skeletal and Muscular Disorders

9,02E-03-9,02E-03

TPT1, RPS4X, RPS3A, VIM, TUBA1B

Cellular Movement

1,38E-02-1,38E-02

VIM

Gene Expression

2,36E-02-3,13E-02

PABPC1, PLK1