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Table 2 Univariate Cox regression (OS)

From: Prognostic stratification of patients with advanced renal cell carcinoma treated with sunitinib: comparison with the Memorial Sloan-Kettering prognostic factors model

  Median OS (95% CI) HR (95% CI) p
Metastatic sites    0.004
   1 NR 1  
   >1 13.8 (10.4-17.3) 3.55 (1.50-8.36)  
Time between diagnosis/surgery and Sunitinib initiation    0.001
   <= 12 months 11.6 (8.2-14.9) 1  
   >12 months NR 0.36 (0.19-0.66)  
Performance Status    0.023
   <= 1 17.4 (10.2-24.6) 1  
   >1 7.6 (0-18.5) 2.32 (1.12-4.80)  
Hb    0.035
   <13 for Males, <11.5 for Females 14.3 (11.3-17.3) 1  
   >= 13 for Males, >= 11.5 for Females NR 0.51 (0.28-0.95)  
Ca    0.538
   <10 17.4 (8.3-26.6) 1  
   >= 10 15.1 (8.4-21.7) 1.29 (0.57-2.90)  
LDH    0.063
   Normal NR 1  
   Abnormal 13.8 (8.7-18.9) 1.78 (0.97-3.26)  
ALP    0.004
   Normal 22.3 1  
   Abnormal 10.7 (6.5-15) 2.46 (1.34-4.50)  
Nephrectomy    0.001
   No 8.9 (3.8-14.2) 1  
   Yes 22.3 0.36 (0.19-0.65)  
  1. NR: not reached