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Table 2 Univariate Cox regression (OS)

From: Prognostic stratification of patients with advanced renal cell carcinoma treated with sunitinib: comparison with the Memorial Sloan-Kettering prognostic factors model

 

Median OS (95% CI)

HR (95% CI)

p

Metastatic sites

  

0.004

   1

NR

1

 

   >1

13.8 (10.4-17.3)

3.55 (1.50-8.36)

 

Time between diagnosis/surgery and Sunitinib initiation

  

0.001

   <= 12 months

11.6 (8.2-14.9)

1

 

   >12 months

NR

0.36 (0.19-0.66)

 

Performance Status

  

0.023

   <= 1

17.4 (10.2-24.6)

1

 

   >1

7.6 (0-18.5)

2.32 (1.12-4.80)

 

Hb

  

0.035

   <13 for Males, <11.5 for Females

14.3 (11.3-17.3)

1

 

   >= 13 for Males, >= 11.5 for Females

NR

0.51 (0.28-0.95)

 

Ca

  

0.538

   <10

17.4 (8.3-26.6)

1

 

   >= 10

15.1 (8.4-21.7)

1.29 (0.57-2.90)

 

LDH

  

0.063

   Normal

NR

1

 

   Abnormal

13.8 (8.7-18.9)

1.78 (0.97-3.26)

 

ALP

  

0.004

   Normal

22.3

1

 

   Abnormal

10.7 (6.5-15)

2.46 (1.34-4.50)

 

Nephrectomy

  

0.001

   No

8.9 (3.8-14.2)

1

 

   Yes

22.3

0.36 (0.19-0.65)

 
  1. NR: not reached