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Table 2 Influence of 24 h MTA on the percentage cells in G1, S and G2/M phase.

From: In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells

  Condition G1phase S phase G2/M phase
   Mean SD   mean SD   mean SD  
CAL-27 24 h 0 nM MTA 49.3 2.2   34.3 2.5   10.8 2.4  
  24 h 50 nM MTA → 0 h 30.4 13.7   56.2 14.1   8.9 3.8  
  24 h 50 nM MTA → 1 h 30.9 12.9   54.5 12.3 * 9.5 4.0  
  24 h 50 nM MTA → 4 h 30.1 9.8 * 53.5 7.5 * 10.8 1.6  
  24 h 50 nM MTA → 8 h 29.0 0.1 * 49.1 2.4 * 15.2 2.0  
  24 h 50 nM MTA → 24 h 41.5 7.9   38.9 6.8   9.2 8.1  
A549 24 h 0 nM MTA 49.5 3.1   37.1 1.3   11.3 0.8  
  24 h 100 nM MTA → 0 h 23.3 6.1 * 66.5 6.2 * 7.2 1.5 *
  24 h 100 nM MTA → 1 h 25.4 4.2 * 65.8 4.6 * 5.4 1.1 *
  24 h 100 nM MTA → 4 h 23.1 5.5 * 68.0 6.3 * 7.9 2.9  
  24 h 100 nM MTA → 8 h 16.4 0.4 * 71.3 1.5 * 8.5 2.1  
  24 h 100 nM MTA → 24 h 57.1 18.8   38.2 0.8   12.4 0.9  
  1. Cell cycle analysis was performed 0, 1, 4, 8 or 24 h after drug wash out. *: p < 0.05 vs. untreated control