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Table 1 Expression and distribution of angiogenic molecules in HCC tissue arrays

From: Mechanism of endothelial progenitor cell recruitment into neo-vessels in adjacent non-tumor tissues in hepatocellular carcinoma

  HC AT HCC
  (-) (+) (++) Positive Percent (-) (+) (++) Positive Percent (-) (+) (++) Positive Percent
VEGF-A 35 3 6 20.5% 43 9 46 56.1%** 41 29 27 57.7%^^##
bFGF 27 4 13 38.6% 29 13 55 70.1%** 32 41 23 66.7%^^##
TGF-β 20 8 16 54.5% 11 4 83 88.8%** 14 15 68 85.6%^^#
MCP-1 20 8 8 44.4% 32 21 44 67.0%* 59 21 17 39.2%##
TSP-1 38 4 1 11.6% 43 14 41 56.1%** 37 33 27 61.9%^^##
MMP-9 28 7 9 36.4% 25 13 59 74.2%** 40 23 35 59.2%^##
TIMP-1 24 2 13 38.5% 63 14 17 33.0% 69 10 17 28.1%
TIMP-2 21 6 17 52.3% 19 13 66 80.6%** 26 37 35 73.5%^^##
Endostatin 23 9 10 45.2% 14 9 75 85.7%** 37 21 40 62.2%##
COX-2 25 9 10 43.2% 7 39 51 92.8%** 9 46 43 90.8%^^
NOS-2 32 9 3 27.3% 37 21 40 62.2%** 43 30 25 56.1%^^
  1. *p < 0.05, **p < 0.01, AT versus HC; # p < 0.05, ## p < 0.01, HCC versus AT, ^p < 0.05; ^^p < 0.01, HCC versus HC