Figure 2

Immunohistochemical staining of MMP-9, TIMP-1, TIMP-2, endostatin, COX-2, and NOS-2 in tissues. Representative sections showing immunohistochemical staining of MMP-9 (A, B, and C), TIMP-1 (D, E, and F), TIMP-2 (G, H, and I), endostatin (J, K, and L), COX-2 (M, N, and O), and NOS-2 (P, Q, and R) in healthy controls (A, D, G, J, M, and P), adjacent non-tumor tissues (B, E, H, K, N, and Q) and tumor tissues (C, F, I, L, O, and R). The signals were detected by DAB staining.