Figure 3

Differences in gene expression and metabolite concentrations. Differences in intracellular choline metabolism, choline transport and glycine formation between basal-like and luminal-like xenografts. Red: higher gene expression/metabolite concentration in basal-like xenografts. Blue: higher gene expression/metabolite concentration in luminal-like xenografts. White: Non-significant difference in expression/concentration. Log2-fold difference between models is indicated by color intensity. Only significantly differentially expressed genes are illustrated at each EC number, which represents specific enzymatic reactions. The metabolites which were measured with HR MAS MRS are outlined with a thicker line.