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Table 2 Percent positivity analyses for each probe across all histological categories (Normal - n = 21; CIN1 - n = 19; CIN2 - n = 27; CIN3 - n = 20; SCC - n = 19)

From: Analysis of genetic copy number changes in cervical disease progression

Threshold = 4 Cells % Positive cases Normal % Positive cases CINa1 % Positive cases CINa2 % Positive cases CINa3 % Positive cases SCCb
8q24 gain 4.8 26.3 96.3 100.0 100.0
3q26 gain 0.0 31.6 81.5 95.0 100.0
Xp22 gain 0.0 10.5 70.4 80.0 100.0
20q13 gain 0.0 21.1 74.1 70.0 100.0
CEPc3 gain 0.0 15.8 66.7 75.0 68.4
CEPc15 gain 4.8 10.5 63.0 65.0 68.4
Ratio 3q26/CEPc3 > 1 0.0 21.1 51.9 75.0 89.5
Ratio
3p14/CEPc3 < 1
9.5 5.6 63.0 75.0 100.0
3p14 < 1 loss 9.5 0.0 33.3 30.0 89.5
  1. a = cervical intraepithelial neoplasia
  2. b = squamous cell carcinoma
  3. c = centromeric probe