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Table 1 Characteristics of the study population (n = 124) and overall survival

From: Genotypes and haplotypes of the VEGF gene and survival in locally advanced non-small cell lung cancer patients treated with chemoradiotherapy

Characteristics

No. of Patients (%)

No. of Deaths (%)*

P †

MST (95% CI, month)

P ‡

Age

  

0.456

 

0.468

   ≤ 60 years

55 (44.4)

39 (70.9)

 

21.0 (13.0-32.0)

 

   > 60 years

69 (56.6)

53 (76.8)

 

18.0 (13.0-26.0)

 

Gender

  

0.175

 

0.046

   Female

57 (46.0)

39 (68.4)

 

26.0 (17.0-38.0)

 

   Male

67 (54.0)

53 (79.1)

 

17.0 (12.0-22.0)

 

Smoke

  

0.752

 

0.679

   Ever

114 (91.9)

85 (74.6)

 

20.0 (16.0-26.0)

 

   Never

10 (8.1)

7 (70.0)

 

16.0 (11.0-18.0)

 

Pack -year

  

0.542

 

0.861

   ≤ 40

60 (48.4)

46 (75.0)

 

19.0 (14.0-29.0)

 

   > 40

64 (51.6)

46 (73.0)

 

20.0 (13.0-29.0)

 

Histology

  

0.828

 

0.632

   Adenocarcinoma

40 (32.3)

31 (77.5)

 

20.0 (17.0-31.0)

 

   Squamous cell

38 (31.6)

28 (73.7)

 

16.0 (12.0-25.0)

 

   Others

46 (37.1)

33 (71.7)

 

24.0 (13.0-36.0)

 

KPS

  

0.175

 

0.067

   90-100

38 (30.7)

24 (66.2)

 

22.0 (16.0-39.0)

 

   80

67 (54.0)

53 (79.1)

 

20.0 (14.0-27.0)

 

   < 80

19 (15.3)

15 (79.0)

 

13.0 (8.0-29.0)

 

Stage

  

0.057

 

0.088

   IIIa

52 (41.9)

34 (65.4)

 

20.0 (16.0-39.0)

 

   IIIb

72 (58.1)

58 (80.6)

 

17.0 (13.0-23.0)

 

Chemotherapy

  

0.186

 

0.766

   Yes

112 (90.3)

85 (75.9)

 

20.0 (16.0-26.0)

 

   No

12 (9.7)

7 (58.3)

 

17.0 (11.0-44.0)

 

Radiotherapy dose

  

0.360

 

0.857

   < 70Gy

59 (47.6)

46 (78.0)

 

21.0 (16.0-33.0)

 

   ≥ 70Gy

65 (52.4)

46 (70.8)

 

17.0 (12.0-24.0)

 
  1. Abbreviations: MST, median survival time.
  2. * Percentage of deaths in each stratum.
  3. † Chi -square test for difference in the distribution of deaths.
  4. ‡ Log-rank test for survival time in the univariate analysis.