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Figure 7 | BMC Cancer

Figure 7

From: LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells

Figure 7

Western blot analysis of Bcl-2 family members (Bak1, Bcl-2, and Bax) and p-p53. The expression of Bak1, Bax, Bcl-2, and β-actin proteins in SNU-719 cells was investigated. Sequential treatment with 5-FU followed by LY2940002 significantly reduced the expression of Bcl-2 protein but slightly increased the expression of Bak1. However, there was no change in the expression of Bax protein.

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