Table 6 Interactions between cigarette smoking and the genetic variants of CYP1A1 and GSTM1 in non-small cell lung cancer with or without promoter hypermethylations of the p16, DAPK and RARβ genes

-

1.41

2.05

2.12*

1.96

1.18

1.03

(0.64-3.08)

(0.94-4.47)

(0.99-4.52)

(0.84-4.59)

(0.50-2.81)

(0.41-2.56)

+

0.97

1.48

1.12

1.88

1.19

1.61

(0.40-2.34)

(0.63-3.47)

(0.47-2.69)

(0.76-4.61)

(0.48-2.97)

(0.66-3.94)

-

1.44

2.14*

2.07

2.64*

1.69

1.75

(0.66-3.12)

(0.99-4.63)

(0.97-4.40)

(1.16-5.99)

(0.75-3.82)

(0.76-4.03)

+

1.00

1.00

1.00

1.00

1.00

1.00

(reference)

(reference)

(reference)

(reference)

(reference)

(reference)

Aa+aa

5.16*

8.28**

4.10**

2.73

1.58

2.82

(1.45-18.35)

(2.38-28.75)

(1.43-11.76)

(0.97-7.64)

(0.54-4.68)

(0.87-9.16)

AA

4.75*

6.57**

3.50*

2.60

2.16

3.29

(1.35-16.65)

(1.91-22.64)

(1.22-10.01)

(0.95-7.11)

(0.77-6.02)

(1.07-10.11)

Aa+aa

0.94

0.85

0.91

1.20

1.39

1.38

(0.24-3.68)

(0.25-2.88)

(0.31-2.70)

(0.47-3.08)

(0.52-3.72)

(0.48-3.96)

AA

1.00

1.00

1.00

1.00

1.00

1.00

(reference)

(reference)

(reference)

(reference)

(reference)

(reference)

-

17.84**

17.41**

8.18**

4.43**

2.76

4.69*

(3.10-102.64)

(4.21-72.05)

(2.53-26.49)

(1.54-12.78)

(0.88-8.60)

(1.29-17.05)

+

17.62**

12.29**

5.14**

3.09*

3.35*

7.10**

(3.08-100.91)

(2.95-51.21)

(1.55-17.05)

(1.04-9.14)

(1.08-10.39)

(1.98-25.41)

-

6.18**

2.81

2.47

2.24

3.00*

3.68*

(1.14-33.56)

(0.77-10.20)

(0.79-7.72)

(0.85-2.90)

(1.05-8.55)

(1.15-11.77)

+

1.00

1.00

1.00

1.00

1.00

1.00

(reference)

(reference)

(reference)

(reference)

(reference)

(reference)