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Table 3 ORs of major risk factors for non-small cell lung cancer.

From: Combined effects of cigarette smoking, gene polymorphisms and methylations of tumor suppressor genes on non small cell lung cancer: a hospital-based case-control study in China

Factor

Crude risk

Adjusted risk

 

OR

95% CI

p-value

ORa

95% CI

p-value

Smoking habit(yes/no)

2.21

1.35-3.3.63

<0.01

3.70

1.49-9.19

p < 0.01

Pack years <20

1.00

-

-

1.00

-

-

   20-30

3.27

1.43-7.49

<0.01

3.54

1.11-11.26

p < 0.05

   30-40

3.53

1.72-7.26

<0.01

3.65

1.27-10.50

p < 0.05

   ≥40

7.54

3.95-14.41

<0.01

7.76

3.00-20.11

p < 0.01

x 2test for trend

p < 0.001

p < 0.001

Alcohol habit(yes/no)

1.46

0.92-2.30

>0.05

1.72

0.83-3.53

p > 0.05

Tea habit(yes/no)

1.14

0.69-1.89

>0.05

0.92

0.41-2.09

p > 0.05

Peppery (servings, > 2 times/week, yes/no)

0.61

0.38-0.98

<0.05

0.35

0.16-0.76

p < 0.01

Fruit (servings, > 2 times/week, yes/no)

0.28

0.14-0.58

<0.01

0.16

0.06-0.43

p < 0.01

Dust exposureb (yes/no)

3.55

2.08-6.04

<0.01

2.06

0.93-4.57

p > 0.05

Toxin exposureb (yes/no)

1.31

0.79-2.18

>0.05

0.68

0.30-1.56

p > 0.05

Lung cancer in firstdegree relatives (yes/no)

1.35

0.63-2.88

>0.05

1.44

0.41-5.06

p > 0.05

CYP1A1((Aa + aa)/AA)c

1.03

0.65-1.62

>0.05

0.83

0.42-1.65

p > 0.05

GSTM1(null/power)d

1.55

0.98-2.46

>0.05

1.13

0.57-2.24

p > 0.05

  1. a adjusted for sex, age, alcohol habit, tea habit, smoking habit and history of lung cancer in first-degree relatives.
  2. b cumulative exposure ≥3 months/year or continuous exposure ≥1 months/year.
  3. c AA = homogeneity wild genotype, Aa = heterogeneity genotype, aa = homogeneity variant genotype
  4. d - = null type, + = power