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Table 4 Effect of D4a and D5 determining mtSNPs on breast cancer and thyroid cancer

From: Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer

mtSNP CCS of breast cancer P value CCS of thyroid cancer P value
  Controls Cases OR   Controls Cases OR  
  (N = 114) (N = 104) (95%CI)   (N = 138) (N = 100) (95%CI)  
C10400T (T489C) 60 69 1.77(1.03-3.07) 0.040* 70 55 1.19(0.71-1.99) 0.514
T16362C+C10400T(T489C) 30 35 1.42(0.79-2.54) 0.237 38 36 1.48(0.85-2.57) 0.164
A10397G+T16362C+C10400T(T489C) 4 13 3.93(1.24-12.46) 0.013* 6 6 1.40(0.44-4.49) 0.565
G16129A+T16362C+C10400T(T489C) 6 4 0.72(0.20-2.63) 0.617 6 12 3.00(1.09-8.29) 0.028*
A10397G+C10400T(T489C) 5 13 3.11(1.07-9.06) 0.030* 8 6 1.04(0.35-3.09) 0.948
A10397G 5 13 3.11(1.07-9.06) 0.030* 8 6 1.04(0.35-3.09) 0.948
A10398G 69 76 1.77(1.00-3.14) 0.050* 74 66 1.08(0.64-1.83) 0.766
T16362C 37 37 1.15(0.66-2.01) 0.627 50 43 1.33(0.78-2.25) 0.291
G16129A 27 31 1.53(0.84-2.78) 0.165 28 28 1.53(0.84-2.79) 0.166
  1. P values were estimated by "chi-square test"; (*) indicated statistical significant (P < 0.05). OR indicates odds ratio; 95% CI, 95% confidence interval.