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Table 4 Effect of D4a and D5 determining mtSNPs on breast cancer and thyroid cancer

From: Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer

mtSNP

CCS of breast cancer

P value

CCS of thyroid cancer

P value

 

Controls

Cases

OR

 

Controls

Cases

OR

 
 

(N = 114)

(N = 104)

(95%CI)

 

(N = 138)

(N = 100)

(95%CI)

 

C10400T (T489C)

60

69

1.77(1.03-3.07)

0.040*

70

55

1.19(0.71-1.99)

0.514

T16362C+C10400T(T489C)

30

35

1.42(0.79-2.54)

0.237

38

36

1.48(0.85-2.57)

0.164

A10397G+T16362C+C10400T(T489C)

4

13

3.93(1.24-12.46)

0.013*

6

6

1.40(0.44-4.49)

0.565

G16129A+T16362C+C10400T(T489C)

6

4

0.72(0.20-2.63)

0.617

6

12

3.00(1.09-8.29)

0.028*

A10397G+C10400T(T489C)

5

13

3.11(1.07-9.06)

0.030*

8

6

1.04(0.35-3.09)

0.948

A10397G

5

13

3.11(1.07-9.06)

0.030*

8

6

1.04(0.35-3.09)

0.948

A10398G

69

76

1.77(1.00-3.14)

0.050*

74

66

1.08(0.64-1.83)

0.766

T16362C

37

37

1.15(0.66-2.01)

0.627

50

43

1.33(0.78-2.25)

0.291

G16129A

27

31

1.53(0.84-2.78)

0.165

28

28

1.53(0.84-2.79)

0.166

  1. P values were estimated by "chi-square test"; (*) indicated statistical significant (P < 0.05). OR indicates odds ratio; 95% CI, 95% confidence interval.