Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer

BMC Cancer

Table 3 Effect of haplogroups on breast, colorectal and thyroid cancer occurrences

Haplogroup	CCS of breast cancer			P value	CCS of colorectal cancer			P value	CCS of thyroid cancer			P value
	Controls	Cases	OR		Controls	Cases	OR		Controls	Cases	OR
	(N = 114)	(N = 104)	(95%CI)		(N = 125)	(N = 108)	(95%CI)		(N = 138)	(N = 100)	(95%CI)
M	60	69	1.77(1.03-3.07)	0.040*	61	53	1.01(0.60-1.69)	0.967	70	55	1.19(0.71-1.99)	0.514
D	26	28	1.25(0.67-2.31)	0.482	32	26	0.92(0.51-1.67)	0.788	34	33	1.51(0.85-2.66)	0.157
D4	21	15	0.75(0.36-1.54)	0.427	23	19	0.95(0.48-1.85)	0.873	26	27	1.59(0.86-2.94)	0.135
D4a	6	4	0.72(0.20-2.63)	0.617	9	6	0.76(0.26-2.20)	0.610	6	12	3.00(1.09-8.29)	0.028*
D5	5	13	3.11(1.07-9.06)	0.030*	9	7	0.89(0.32-2.49)	0.829	8	6	1.04(0.35-3.09)	0.948
G	2	7	4.04(0.82-19.91)	0.065	3	0	-	0.105	3	1	0.46(0.05-4.44)	0.487
M8	8	15	2.23(0.91-5.51)	0.075	8	9	1.33(0.49-3.58)	0.571	11	6	0.74(0.26-2.06)	0.560
M7	16	8	0.51(0.21-1.25)	0.135	13	9	0.78(0.32-1.91)	0.591	15	11	1.01(0.44-2.31)	0.975
M10a	2	5	2.83(0.54-14.90)	0.202	1	3	3.54(0.36-34.57)	0.246	3	0	-	0.138
N
A	10	4	0.42(0.13-1.37)	0.138	10	9	1.05(0.41-2.68)	0.926	11	9	1.14(0.46-2.87)	0.778
N9	3	4	1.48(0.32-6.78)	0.611	5	7	1.66(0.51-5.40)	0.393	4	5	1.76(0.46-6.74)	0.402
R	41	27	0.62(0.35-1.12)	0.111	48	36	0.80(0.47-1.37)	0.422	52	27	0.61(0.35-1.07)	0.084
B	23	14	0.69(0.33-1.44)	0.322	24	20	0.96(0.50-1.85)	0.895	26	16	0.82(0.41-1.63)	0.570
B4	16	8	0.51(0.21-1.25)	0.135	17	9	0.58(0.25-1.36)	0.203	19	9	0.62(0.27-1.43)	0.260
B5	7	5	0.77(0.24-2.51)	0.667	7	11	1.91(0.71-5.12)	0.191	7	7	1.41(0.48-4.15)	0.533
F	13	11	0.92(0.39-2.15)	0.846	19	16	0.97(0.47-2.00)	0.935	22	11	0.65(0.30-1.41)	0.276

P values were estimated by "chi-square test"; (*) indicated statistical significant (P < 0.05). OR indicates odds ratio; 95% CI, 95%confidence interval.

ISSN: 1471-2407