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Table 4 Correlations between lymphatic vessel density and clinicopathologic features in the laryngeal carcinoma series (N = 50).

From: Prognostic significance of lymphangiogenesis in pharyngolaryngeal carcinoma patients

PHARYNX ILD PLD LVD Lymphatic Invasion
Frequency 90% (45/50) 90% (45/50) 96% (48/50) 58% (29/50)
Mean (S.E.) 19.14 (1.97) 27.41 (2.57) 26.47 (1.92)     
Score range 0-78.39 0-82.17 8.5 -79.34     
  N Mean (S.E) N Mean (S.E) N Mean range p# Absent Present Total p*
Anatomic site              
Hypopharynx 18 19.92 (3.48) 0.8600 18 30.87 (3.91) 0.3470 18 29.67 0.0810 12 6 18 0.0230
Oropharynx 31 19.18 (2.45)   31 25.70 (3.46)   31 22.29   9 22 31  
Total 49    49    49    21 28 49  
pT              
T1-2 11 14.71 (3.53) 0.236 11 27.45 (3.12) 0.993 11 29.18 0.343 4 7 11 0.668
T3-4 39 20.39 (2.30)   39 27.39 (3.11)   39 24.46   17 22 39  
Total 50    50    50    21 29 50  
Nodal involvement              
Free 9 16.30 (3.90) 0.3330 9 26.94 (7.77) 0.3450 9 27.50 0.6550 5 4 9 0.3630
Affected 41 19.77 (2.25)   41 27.51 (2.69)   41 25.06   16 25 41  
Total 50    50    50    21 29 50  
Tumour Stage              
I-II 4 12.12 (7.01) 0.3720 4 19.05 (8.74) 0.3650 4 28.13 0.4280 4 0 4 0.0100
III-IV 41 19.60 (2.29)   41 28.57 (2.99)   41 22.50   14 27 41  
Total 45    45    45    18 27 45  
Recurrence              
No 23 19.19 (2.37) 0.9140 23 26.41 (4.34) 0.7410 23 24.39 0.8480 9 14 23 0.6420
Yes 24 18.73 (3.45)   24 28.24 (3.43)   24 23.63   11 13 24  
Total 47    47    47    20 27 47  
  1. ILD, Intratumoural Lymphatic Density; PLD, Peritumoural Lymphatic Density; LVD, Lymphatic Vessel Density
  2. S.E., Standard Error
  3. p# (U Mann-Whitney); p¥ (t Student); p* (chi square)
  4. Frequencies (cases with lymph vessels), mean values and score ranges of ILD, PLD and LVD in pharyngeal population (N=50). Comparison of mean ILD, PLD and LVD values among different categories of clinico-pathological features. Distribution of tumours according to lymphatic invasion (LI) and clinicopathological features.