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Table 3 Correlations between lymphatic vessel density and clinicopathologic features in the laryngeal carcinoma series (N = 54).

From: Prognostic significance of lymphangiogenesis in pharyngolaryngeal carcinoma patients

LARYNX ILD PLD LVD) Lymphatic Invasion
Frequency 57.41% (31/54) 55.56% (30/54) 87.04% (47/54) 28.30% (15/53)
Mean (S.E.) 10.59 (1.65) 18.47 (2.03) 18.98 (1.56)     
Score range 0-41.56 0-60.45 0-44.71     
  N Mean range p# N Mean (S.E) N Mean (S.E) Absent Present Total p*
Anatomic site              
Glottis 30 23.45 0.028 30 15.22 (2.43) 0.073 30 16.14 (2.06) 0.042 23 6 29 0.176
Supraglottis 24 32.56   24 22.54 (3.30)   24 22.52 (2.24)   15 9 24  
Total 54    54    54    38 15 53  
pT              
T1-2 28 22.05 0.006 28 15.95 (2.85) 0.2 28 15.98 (2.38) 0.044 25 3 28 0.003
T3-4 26 33.37   26 21.19 (2.86)   26 22.20 (1.84)   13 12 25  
Total 54    54    54    38 15 53  
Nodal involvement              
Free 38 25.38 0.112 38 16.63 (2.23) 0.165 38 17.72 (1.81) 0.219 30 8 38 0.062
Affected 16 32.53   16 22.85 (4.27)   16 21.96 (3.03)   8 7 15  
Total 54    54    54    38 15 53  
Tumour Stage              
I-II 24 20.92 0.004 24 13.95 (2.52) 0.045 24 15.05 (2.35) 0.023 20 4 24 0.073
III-IV 30 32.77   30 22.09 (2.92)   30 22.12 (1.94)   17 11 28  
Total 54    54    54    37 15 52  
Recurrence              
No 43 28.35 0.169 43 17.02 (2.28) 0.218 43 18.60 (1.80) 0.685 29 13 42 0.492
Yes 10 21.20   10 23.55 (4.7)   10 20.28 (3.57)   8 2 10  
Total 53    53    53    37 15 52  
  1. ILD, Intratumoural Lymphatic Density; PLD, Peritumoural Lymphatic Density; LVD, Lymphatic Vessel Density
  2. S.E., Standard Error
  3. p# (U Mann-Whitney); p¥ (t Student); p* (chi square)
  4. Frequencies (cases with lymph vessels), mean values and score ranges of ILD, PLD and LVD in laryngeal carcinoma population (N=54). Comparison of mean ILD, PLD and LVD values among different categories of clinico-pathological features. Distribution of tumours according to lymphatic invasion (LI) and clinicopathological features.