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Figure 2 | BMC Cancer

Figure 2

From: Mutations in the WTX- gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers

Figure 2

Frameshift mutations in the WTX -gene are expressed on the mRNA level. (A) CRCs (ID #1, #2 and #42) expressed WTX mRNA. (B) One of the two CRCs with MSI-H and a genomic frameshift mutation in the WTX-gene displayed expression of the mutated allele on the level of mRNA (ID #1) whereas the other tumor (ID #2) as well as MSS-CRCs (ID #42) harbored wild type mRNA indicated by the presence of only T6-repeats.

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