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Table 1 EMT-associated genes overexpressed in CD44+/CD24- cells compared to CD44-/CD24+ cells.

From: SLUG/SNAI2 and Tumor Necrosis Factor Generate Breast Cells With CD44+/CD24- Phenotype

Gene Symbol Gene name GenBank number Fold- change
AKT3 V-AKT murine thymoma oncogene homolog 3 NM_005465 2.0
BDNF Brain-derived neurotropic factor NM_001709 28.8
CDH2 Cadherin-2 (N-cadherin) NM_001792 29.8
CTGF Connective tissue growth factor NM_001901 33.5
DAB2 Disabled homolog 2 NM_001343 2.4
FGFR1 Fibroblast growth factor receptor 1 NM_023105 2.6
FYN FYN oncogene related to SRC, FGR, YES NM_002037 10.1
HMGA2 High mobility AT-hook 2 NM_003483 24.4
IL8 Interleukin 8 NM_000584 4.8
ILK Integrin-linked kinase NM_004517 2.1
ITF2/TCF4 Transcription factor 4 NM_003199 2.1
JAG1 Jagged 1 NM_000214 2.6
JAK2 Janus kinase 2 NM_004972 2.0
MAP4K4 Mitogen activated protein kinase kinase kinase kinase NM_017792 2.0
MMP-2 Matrix metalloproteinase 2 NM_004530 14.5
NR2F1/COUP-TF1 Nuclear receptor subfamily 2, group F, member 1 NM_005654 17.9
Periostin Periostin, osteoblast specific factor NM_006475 81.7
PIK3R1 PI3 kinase regulatory subunit (p85) NM_181523 2.7
PRKC alpha Protein kinase C alpha NM_002737 6.8
S100A4 S100, calcium binding protein A4 NM_002961 7.0
SMAD3 SMAD, mother against DPP homolog 3 NM_005902 2.0
SMAD7 SMAD, mother against DPP homolog 7 NM_005904 3.4
SMURF2 SMAD-specific E3 ubiquitin ligase 2 NM_022739 2.1
SNAI2/SLUG SNAIL homolog 2 NM_003068 2.3
SPARC Secreted protein cysteine-rich (osteonectin) NM_003118 107.7
TGFβ1 Transforming growth factor beta 1 NM_011577 4.6
TGFβ2 Transforming growth factor beta 2 NM_003238 3.4
TWIST2 TWIST homology 2 NM_057179 4.8
Wnt5A Wingless type, MMTV integration family member, type 5A NM_003392 6.9
Wnt5B Wingless type, MMTV integration family member, type 5B NM_030775 60.1
ZEB-1/TCF8 Transcription factor 8 NM_024285 27.8
ZEB-2/ZFHX1B Zinc finger E-box binding homeobox 2 NM_014795 8.3