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Table 1 EMT-associated genes overexpressed in CD44+/CD24- cells compared to CD44-/CD24+ cells.

From: SLUG/SNAI2 and Tumor Necrosis Factor Generate Breast Cells With CD44+/CD24- Phenotype

Gene Symbol

Gene name

GenBank number

Fold- change

AKT3

V-AKT murine thymoma oncogene homolog 3

NM_005465

2.0

BDNF

Brain-derived neurotropic factor

NM_001709

28.8

CDH2

Cadherin-2 (N-cadherin)

NM_001792

29.8

CTGF

Connective tissue growth factor

NM_001901

33.5

DAB2

Disabled homolog 2

NM_001343

2.4

FGFR1

Fibroblast growth factor receptor 1

NM_023105

2.6

FYN

FYN oncogene related to SRC, FGR, YES

NM_002037

10.1

HMGA2

High mobility AT-hook 2

NM_003483

24.4

IL8

Interleukin 8

NM_000584

4.8

ILK

Integrin-linked kinase

NM_004517

2.1

ITF2/TCF4

Transcription factor 4

NM_003199

2.1

JAG1

Jagged 1

NM_000214

2.6

JAK2

Janus kinase 2

NM_004972

2.0

MAP4K4

Mitogen activated protein kinase kinase kinase kinase

NM_017792

2.0

MMP-2

Matrix metalloproteinase 2

NM_004530

14.5

NR2F1/COUP-TF1

Nuclear receptor subfamily 2, group F, member 1

NM_005654

17.9

Periostin

Periostin, osteoblast specific factor

NM_006475

81.7

PIK3R1

PI3 kinase regulatory subunit (p85)

NM_181523

2.7

PRKC alpha

Protein kinase C alpha

NM_002737

6.8

S100A4

S100, calcium binding protein A4

NM_002961

7.0

SMAD3

SMAD, mother against DPP homolog 3

NM_005902

2.0

SMAD7

SMAD, mother against DPP homolog 7

NM_005904

3.4

SMURF2

SMAD-specific E3 ubiquitin ligase 2

NM_022739

2.1

SNAI2/SLUG

SNAIL homolog 2

NM_003068

2.3

SPARC

Secreted protein cysteine-rich (osteonectin)

NM_003118

107.7

TGFβ1

Transforming growth factor beta 1

NM_011577

4.6

TGFβ2

Transforming growth factor beta 2

NM_003238

3.4

TWIST2

TWIST homology 2

NM_057179

4.8

Wnt5A

Wingless type, MMTV integration family member, type 5A

NM_003392

6.9

Wnt5B

Wingless type, MMTV integration family member, type 5B

NM_030775

60.1

ZEB-1/TCF8

Transcription factor 8

NM_024285

27.8

ZEB-2/ZFHX1B

Zinc finger E-box binding homeobox 2

NM_014795

8.3