Figure 3
From: Simplifying the detection of MUTYH mutations by high resolution melting analysis
Different plot and sequence traces are indicated for MUTYH exon 12 mutations. (a1) (a2) The melting profile with sensitivity 0,3. The figures shows that mutations were clearly distinct from the wild type controls. Melt curves of each mutation, green: R354GfsX40 heterozygotes, red: G338H non-pathogenic heterozygotes polymorphism against the wild type (blue). (b) Sequencing electropherograms show a G338H heterozygous polymorphism and a wild type.