Figure 1
From: Residual γH2AX foci as an indication of lethal DNA lesions
Development of γH2AX after MNNG treatment. Flow cytometric analysis was used to detect γH2AX formation in V79 cells exposed to MNNG for 30 min and then allowed 1 h to develop γH2AX foci. Single cells were fixed and analyzed for γH2AX antibody binding in relation to DNA content using flow cytometry. Cells that expressed control levels of γH2AX are contained within the boxes and are given as percentages.