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Table 5 Tumor characteristics in cases with total cases and rare alleles

From: Short rare hTERT-VNTR2-2nd alleles are associated with prostate cancer susceptibility and influence gene expression

Characteristic 2006 AMC* 2006 NCC** 2005 AMC* This study Rare alleles χ2-value*** (Pvalue)
Age       
   Mean 63.9 (42-78) 64.1 (46-80) 64.3 (40-83) 67.9 (50-88) 64.7 (55-81)  
T-stage       
   T1 0 (0.0%) 0 (0.0%) 130 (41.0%) 42 (13.2%) 0 (0.0%) 6.0132 (df = 3)
   T2 116 (62.4%) 52 (63.4%) 183 (57.7%) 139 (43.8%) 3 (42.9%) P = 0.1110
   T3 68 (36.6%) 29 (35.4%) 4 (1.3%) 95 (30.0%) 1 (14.3%)  
   T4 2 (1.1%) 1 (1.2%) 0 (0.0%) 41 (12.9%) 3 (42.9%)  
N-stage       
   N0 182 (97.8%) 45 (91.8%) 291 (91.8%) 265 (85.8%) 3 (42.9%) 6.7334 (df = 1)
   N1 4 (2.2%) 4 (8.2%) 26 (8.2%) 44 (14.2%) 4 (57.1%) P = 0.0095
M-stage       
   M0 158 (84.9%) 45 (91.8%) 280 (88.3%) 247 (75.5%) 3 (37.5%) 4.1265 (df = 1)
   M1 28 (15.1%) 4 (8.2%) 37 (11.7%) 80 (24.5%) 5 (62.5%) P = 0.0422
Gleason score       
   2-6 34 (18.3%) 22 (31.9%) 126 (39.8%) 71 (23.5%) 1 (12.5%) 2.839 (df = 2)
   7 108 (58.0%) 33 (47.8%) 98 (30.9%) 95 (31.5%) 1 (12.5%) P = 0.2418
   8-10 44 (23.7%) 14 (20.3%) 93 (29.3%) 136 (45.0%) 6 (75.0%)  
PSA (ng/ml)       
   <10 110 (59.1%) 41 (49.4%) 142 (44.8%) 29 (34.1%) 0 (0.0%) 2.253 (df = 2)
   10-20 57 (30.7%) 21 (25.3%) 102 (32.2%) 8 (9.4%) 0 (0.0%) P = 0.3241
   >20 19 (10.2%) 21 (25.3%) 73 (23.0%) 48 (56.5%) 3 (100%)  
Jewett-Whitmore system       
   A     35 (10.7%) 0 (0.0%) 7.3884 (df = 3)
   B ND ND ND 126 (38.4%) 1 (12.5%) P = 0.0605
   C     67 (20.4%) 1 (12.5%)  
   D     100 (30.5%) 6 (75.0%)  
Tumor grade       
   Well    25 (7.9%) 9 (3.0%) 0 (0.0%) 0.6087 (df = 2)
   Moderate ND ND 101 (31.9%) 62 (20.5%) 1 (12.5%) P = 0.7376
   Poor    191 (60.3%) 231 (76.5%) 7 (87.5%)  
  1. *Data of Asan Medical Center, Korea; ** Data of National Cancer Center, Korea; *** Pearson's Chi-squared test was performed between total cases with prostate cancer and cases with rare alleles used in this study.