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Figure 2 | BMC Cancer

Figure 2

From: Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1

Figure 2

Cinnamon extract treatment induces active cell death in melanoma cells. At the indicated time periods after treatment of cinnamon extract, cells were stained with Annexin V and 7-ADD. Double positive (Annexin V+ and 7-ADD+) (A) or Annexin V+ positive (B) populations were analyzed by FACS. Gene expression (C) and protein (D) level of pro-apoptotic molecules such as Bad, Bim, Bax and Bak were measured by quantitative real-time PCR or immunoblotting, respectively. Error bars indicated SD. One (*), two (**) or three asterisks (***) indicate p < 0.05, p < 0.005 or p < 0.001, respectively. Data are representative of three independent experiments.

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