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Table 7 Overall Survival: Univariate and Multivariate Analysis in Patients without Poor Risk Cytogenetics (N = 20)

From: Histone H4 acetylation by immunohistochemistry and prognosis in newly diagnosed adult acute lymphoblastic leukemia (ALL) patients

Patient Characteristic

HR on Univariate Analysis (95% confidence interval with p-value)

HR on Multivariate Analysis (95% confidence interval with p-value)

Histone acetylation (Positive versus negative

0.25 (0.09-0.69), p = 0.007

0.24 (0.08-0.68), p = 0.007

Age (>35 years vs. ≤35 years)

2.66 (0.93-7.61), p = 0.07

2.49 (0.80-7.79), p = 0.12

White blood count (>20,000/μL versus ≤20,000/μL)

3.77 (1.11-12.8), p = 0.033

3.83 (1.06-13.9), p = 0.41