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Table 3 Relapse-Free Survival: Univariate and Multivariate Analyses for All Patients (N = 46)

From: Histone H4 acetylation by immunohistochemistry and prognosis in newly diagnosed adult acute lymphoblastic leukemia (ALL) patients

Patient Characteristic

HR on Univariate Analysis (95% confidence interval with p-value)

HR on Multivariate Analysis (95% confidence interval with p-value)

Histone acetylation (Positive versus negative)

0.42 (0.16-1.13), p = 0.09

0.55 (0.19-1.59), p = 0.27

Age (>35 years vs. ≤35 years)

1.81 (0.75-4.34), p = 0.19

1.39 (0.35-5.72), p =0 .65

White blood count (>20,000/μL versus ≤20,000/μL)

3.88 (1.54-9.79), p = 0.004

15.0 (2.41-89.5), p = 0.003

Poor risk cytogenetics versus others

2.36 (0.93-6.03), p = 0.07