Figure 1

RT-PCR analysis of HIF1α mRNA isoforms in benign prostate hyperplasia (B, Fig. 1a-f), NE differentiated prostate cancer (M1, Fig.1a-f)) and non NE differentiated prostate cancer (M2, Fig. 1a-f)). K (Fig. 1a-f) and T (Fig. 1b) correspond to control and testis tissue, respectively. HIF1α isoforms in LNCaP cells (Fig. 1g), Lane 1 represents HIF1α1.1, lane 2 represents HIF1α1.2, and lane 3 represents HIF1α1.3. Lane 4: bands detected with primers sets located in exons 10 and 13, lane 5 includes bands from primers located in exon 12 and lane 6 corresponds to bands detected with primers located in exons 13 and 15