Skip to main content

Advertisement

Table 2 Haplotype Analysis of TLR9 rs187084 (T > C) and rs5743836 (T > C) and endometrial cancer risk

From: Toll-Like Receptor (TLR) and Nucleosome-binding Oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk

Gene Haplotype Cases n (%) Controls n (%) OR (95% CI) p value
TLR9 (rs187084 and rs5743836) TT 98 (51.3) 141 (48.5) 1.00 (reference)  
  CT 65 (34.0) 90 (30.9) 1.09 (0.75-1.57)adj^ p = 0.66
     0.99 (0.75-1.31) p = 0.94
  TC 26 (13.6) 39 (13.4) 1.07 (0.63-1.80)adj^ p = 0.76
     0.92 (0.63-1.36) p = 0.68
  CC 2 (1.1) 21 (7.2) 0.10 (0.02-0.46) adj^ p = 0.003
     0.11 (0.03-0.44) p = 0.002
  1. NB: Variant allele is underlined.
  2. ^ Odds Ratio adjusted for age, BMI, diabetes, HBP, history of cancer, HT, smoking and alcohol use.