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Figure 3 | BMC Cancer

Figure 3

From: Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

Figure 3

DISC components are unchanged in VDAC1 knockdown cells. (A) Western blots showing expression of TRAIL receptor DR5, c-FLIP, and FADD, which are of comparable levels in sh-NT control and sh-VDAC1 cells, both before and after TRAIL treatment. (B) Flow cytometry showing cell surface expression of TRAIL receptors DR4 and DR5 in sh-NT and sh-VDAC1 cell lines. All cells show high levels of DR5 expression and relatively low levels of DR4.

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BMC Cancer

ISSN: 1471-2407

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