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Table 5 Association of hormone receptors with gene methylation in lymph nodes metastasis (M)

From: Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers

 

ER (+)

ER (-)

pvalue

PR (+)

PR (-)

pvalue

HIN-1 (M)

35.8 ± 24.3

15.3 ± 13.9

0.008

38.1 ± 24.7

22.5 ± 19.9

0.047

CDH13 (M)

17.8 ± 14.8

29.4 ± 23.8

0.220

18.8 ± 16.5

22.1 ± 18.6

0.565

RIL (M)

35.0 ± 24.2

42.4 ± 31.6

0.474

31.8 ± 25.3

43.6 ± 25.1

0.155

RASSF1A (M)

24.8 ± 20.0

35.7 ± 26.3

0.203

25.5 ± 21.4

29.2 ± 22.1

0.594

RARβ2 (M)

10.2 ± 13.7

18.7 ± 30.7

0.470

11.6 ± 14.7

12.5 ± 22.9

0.881

E-cadherin (M)

8.1 ± 8.6

8.2 ± 11.5

0.975

8.7 ± 9.3

7.1 ± 8.9

0.599