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Table 4 Association of hormone receptors with gene methylation in primary cancers (P)

From: Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers

 

ER (+)

ER (-)

pvalue

PR (+)

PR (-)

pvalue

HIN-1 (P)

41.3 ± 26.1

15.8 ± 13.2

0.001

40.3 ± 25.0

30.1 ± 27.3

0.232

CDH13 (P)

18.8 ± 18.8

21.0 ± 14.0

0.756

21.0 ± 19.4

16.5 ± 15.2

0.440

RIL (P)

33.2 ± 24.9

41.9 ± 24.1

0.380

30.5 ± 25.3

41.5 ± 23.0

0.171

RASSF1A (P)

29.5 ± 20.5

21.9 ± 17.6

0.340

28.6 ± 20.0

27.0 ± 20.5

0.809

RARβ2 (P)

18.2 ± 23.4

11.3 ± 11.6

0.249

17.9 ± 21.2

15.2 ± 22.9

0.706

E-cadherin (P)

7.3 ± 6.6

10.5 ± 15.4

0.602

6.2 ± 4.2

10.4 ± 12.7

0.230