Table 1 Expression fold changes of 84 AM genes in CD34+ cells from CR AML patients
Genes | chemoresistant vs control | chemosensitive vs control | chemoresistant vs chemosensitive | Genes | chemoresistant vs control | chemosensitive vs control | chemoresistant vs chemosensitive |
|---|---|---|---|---|---|---|---|
ABL1 | 1.05 (0.85) | -1.04 (1) | -1.11 (1) | CASP7 | -2.08 (0.14) | -2 (0.03) | -1.26 (0.17) |
AKT1 | -1.55 (0.15) | -1.05 (0.87) | -1.79 (0.18) | CASP8 | -15.74 (0.006) | -19.29 (0.04) | 1.01 (1) |
APAF1 | 1.35 (0.29) | 2.66 (0.08) | -2.38 (0.007) | CASP9 | -1.95 (0.20) | -1.46 (0.08) | -1.61 (0.09) |
BAD | 1.35 (0.26) | 1.47 (0.20) | -1.32 (0.46) | CD27 | -1.49 (0.24) | -2.33 (0.11) | 1.29 (0.99) |
BAG1 | 1.75 (0.34) | 1.55 (0.47) | -1.07 (1) | CD40 | -3.11 (0.02) | -4.89 (0.01) | 1.3 (0.50) |
BAG3 | -41.26 (0.0004) | -76.11 (0.00009) | 1.53 (1) | CD40LG | -16.3 (0.01) | -2.57 (0.04) | -7.67 (0.02) |
BAG4 | -2.34 (0.09) | -2.99 (0.08) | 1.06 (1) | CD70 | -10.31 (0.002) | -17.03 (0.01) | 1.37 (0.62) |
BAK1 | -1.11 (1) | -1.26 (0.47) | -1.06 (1) | CFLAR | -51.86 (0.002) | -22.01 (0.003) | -2.85 (0.03) |
BAX | 1.43 (0.80) | 1.31 (0.73) | -1.11 (1) | CIDEA | -15.74 (0.008) | -19.29 (0.009) | 1.01 (1) |
BCL10 | 3.09 (0.007) | 3.01 (0.007) | 1.01 (1) | CIDEB | 1.26 (0.37) | 2.55 (0.03) | -2.45 (0.001) |
BCL2 | 2.15 (0.12) | 1.9 (0.23) | -1.35 (0.30) | CRADD | -1.24 (0.18) | -1.77 (0.07) | 1.18 (0.52) |
BCL2A1 | -5.19 (0.01) | -2.81 (0.02) | -2.23 (0.004) | DAPK1 | -15.74 (0.0006) | -19.29 (0.0002) | 1.01 (1) |
BCL2L1 | -3.5 (0.007) | 1.06 (0.44) | -4.47 (0.005) | DFFA | 3.11 (0.00008) | 3.01 (0.00009) | 1.01 (1) |
BCL2L10 | -15.74 (0.01) | -19.29 (0.02) | 1.01 (1) | FADD | -5.02 (0.004) | -6.41 (0.004) | 1.06 (1) |
BCL2L11 | 1.36 (0.25) | 1.38 (0.26) | -1.22 (0.72) | FAS | -7.19 (0.01) | -3.53 (0.04) | -2.46 (0.003) |
BCL2L2 | -1.25 (0.24) | -1.04(1) | -1.44 (0.21) | FASLG | -22.58 (0.005) | -4.32 (0.02) | -6.32 (0.01) |
BCLAF1 | 3.12 (0.003) | 3.04(0.002) | 1.01 (1) | GADD45A | -2.09 (0.16) | -2.69 (0.22) | 1.06 (1) |
BFAR | 3.01 (0.0006) | 1.84(0.03) | 1.01 (1) | HRK | -3.75 (0.01) | -6.11 (0.01) | 1.35 (0.30) |
BID | -1.03 (0.93) | 1.16 (0.43) | -1.44 (0.21) | IGF1R | -2.29 (0.08) | -3.16 (0.07) | 1.14 (1) |
BIK | 1.1 (1) | 1.47 (0.34) | -1.61 (0.38) | LTA | -7.34 (0.05) | -4.72 (0.01) | -1.88 (0.12) |
BIRC2 | 3.77 (0.006) | -7.26 (0.004) | 22.63 (0.001) | LTBR | -1.38 (0.25) | -1.13 (0.47) | -1.47 (0.27) |
BIRC3 | -3.02 (0.001) | -10.13 (0.004) | 2.77 (0.001) | MCL1 | 1.51 (0.33) | 1.34 (0.46) | -1.07 (0.51) |
BIRC4 | -11.77 (0.0007) | -15.14 (0.0007) | 1.06 (1) | NAIP | 1.96 (0.13) | 1.39 (0.34) | 1.16 (1) |
BIRC6 | -1.08 (0.85) | 1.04 (0.73) | -1.37 (0.18) | NOD1 | -1.31 (0.36) | -1.09 (0.94) | -1.44 (0.75) |
BIRC8 | -17.71 (0.0005) | -21.71 (0.0002) | 1.01 (1) | NOL3 | -15.74 (0.001) | -10.34 (0.0003) | -1.84 (0.21) |
BNIP1 | -9.17 (0.0008) | -10.41 (0.001) | -1.06 (1) | PYCARD | 1.12 (0.48) | 1.79 (0.07) | -1.93 (0.05) |
BNIP2 | -8.15 (0.005) | -7.52 (0.007) | -1.31 (0.24) | RIPK2 | -1.11 (0.21) | -1.69 (0.48) | 1.26 (0.08) |
BNIP3 | -8.38 (0.02) | -9.71 (0.03) | -1.04 (1) | TNF | 2.08 (0.18) | 2.3 (0.31) | -1.34 (0.29) |
BNIP3L | -3.75 (0.02) | -4.41 (0.01) | -1.03 (1) | TNFRSF10A | -6.13 (0.013) | -4.03 (0.01) | -1.84 (0.13) |
BRAF | -1.09 (0.83) | -1.27 (0.15) | -1.04 (1) | TNFRSF10B | -5.72 (0.016) | -4.92 (0.02) | -1.4 (0.43) |
CARD6 | -15.74 (0.001) | -19.29 (0.0008) | 1.01 (1) | TNFRSF11B | -15.74 (0.007) | -19.29 (0.007) | 1.01 (1) |
CARD8 | -4.55 (0.01) | -3.76 (0.01) | -1.46 (0.19) | TNFRSF1A | 2.42 (0.13) | 1.65 (0.11) | 1.21 (0.76) |
CASP1 | -1.35 (0.45) | 1.06 (0.48) | -1.74 (0.01) | TNFRSF21 | 1.1 (0.29) | -1.48 (0.83) | 1.35 (0.12) |
CASP10 | -5.12 (0.01) | -6.5 (0.012) | 1.05 (1) | TNFRSF25 | 1.07 (1) | 3.61 (0.03) | -4.06 (0.03) |
CASP14 | -25.4 (0.03) | -58.89 (0.0004) | 1.92 (0.02) | TNFRSF9 | -15.74 (0.03) | -18.38 (0.01) | -1.04 (1) |
CASP2 | 1.05 (1) | 1.1 (1) | -1.27 (1) | TNFSF10 | -1.25 (0.12) | 1.45 (0.08) | -2.2 (0.01) |
CASP3 | 1.07 (1) | -1.13 (0.68) | -1.01 (1) | TNFSF8 | -9.04 (0.007) | -10.7 (0.008) | -1.02 (1) |
CASP4 | -1.47 (0.08) | -1.57 (0.09) | -1.13 (0.72) | TP53 | 1.27 (0.20) | 1.2 (0.23) | -1.14 (0.70) |
CASP5 | -12.27 (0.002) | -11.71 (0.002) | -1.27 (0.16) | TP53BP2 | -15.74 (0.02) | -19.29 (0.003) | 1.01 (1) |
CASP6 | 1.2 (0.34) | 1.2 (0.43) | -1.21 (0.99) | TP73 | -53.32 (0.006) | -48.5 (0.006) | -1.33 (0.70) |