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Table 6 Age and habits distribution in relation to alleles in HNSCC and Controls

From: Synergistic effect of stromelysin-1 (matrix metalloproteinase-3) promoter (-1171 5A->6A) polymorphism in oral submucous fibrosis and head and neck lesions

Characteristics HNSCC
(N = 135)
Control
(N = 126)
  6A/6A 5A/6A 5A/5A p-value 5A/5A 6A/6A 5A/6A (p-value)
Age (Yrs)         
Mean ± SD 42 ± 16.5 47 ± 10.8 41 ± 9.86 0.42 17.5 ± 0.7 36.7 ± 12.4 38.8 ± 16 0.41
Tobacco with Areca nut         
Chewer 98(92.45%) 16(69.56%) 4 (66.6%)   2(100%) 71(64.5%) 12(85.7%) 0.12
Non Chewer 8(7.54%) 7(30.43%) 2 (33.3%) 0.003 0 39(35.5%) 2(14.3%)  
Smoking status         
Smoker 88(83.01%) 15(65.21%) 4 (66.6%)   0 47(42.7%) 4(28.6%) 0.11
Non-smoker 18(16.98%) 8(34.78%) 2 (33.3%) 0.037 2(100%) 63(57.3%) 10(71.4%)  
Alcohol Intake         
Drinker 72(67.92%) 14(60.86%) 3 (50%) 0..81 0 25(22.7%) 1(7.1%) 0.24
Non Drinker 34(32.07%) 9(39.1%) 3 (50%)   2(100%) 85(77.3%) 13(92.9%)  
  1. [Data was expressed as mean ± SD and %. Fischer exact test is used for habits in HNSCC cases and control groups]