Table 1 Incidence of pulmonary metastasis in each generation of mouse model during in vivo selection
| Generation |
Macrometastases (mouse numbers) |
Micrometastases (mouse numbers) | Selection periods (weeks) |
|---|---|---|---|
| First | 2/10 | 6/10 | 18 |
| Second | 1/7 | 5/7 | 14 |
| Third | 3/9 | 7/9 | 13 |
| Fourth | 5/9 | 9/9 | 12 |