Table 4 Association of clinical, pathological and genotypic parameters with progression free survival (PFS).
| Parameters | n | Events | %PFS | p |
|---|---|---|---|---|
| Tumor size | ||||
| T2 | 76 | 12 | 62.6 | 0.089 |
| T3-T4 | 19 | 6 | 59.3 | |
| Lymph node involvement | ||||
| N0 | 76 | 10 | 57.31 | 0.0011 |
| N1-N2 | 19 | 8 | 44.7 | |
| Stage | ||||
| IIa | 65 | 8 | 58.2 | 0.0232 |
| IIb | 20 | 6 | 65.1 | |
| IIIa-IIIb | 10 | 4 | 42.3 | |
| RR4M | ||||
| Responders | 35 | 1 | 96.7 | 0.0033 |
| Non-responders | 60 | 17 | 45.6 | |
| rs10046 | ||||
| GG | 18 | 3 | 80.0 | 0.967 |
| AG/AA | 80 | 15 | 81.3 | |
| rs4646 | ||||
| CC | 57 | 7 | 85.7 | 0.0686 |
| AC/AA | 38 | 11 | 50.9 |