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Table 2 CYP19A1 polymorphisms and genotype frequencies

From: A polymorphism at the 3'-UTR region of the aromatase gene defines a subgroup of postmenopausal breast cancer patients with poor response to neoadjuvant letrozole

db-SNP id

Genotype

n (%)

p*

Gene location

Chromosome position**

rs700519

CC

89 (100)

-

Exon 7 (codon 264)

49.295.260

 

CT

0 (0)

   
 

TT

0 (0)

   

rs10046

AA

23 (24.2)

0.127

3'UTR

49.290.278

 

AG

57 (60.0)

   
 

GG

15 (15.8)

   

rs4646

CC

57 (60.0)

0.397

3'UTR

49.290.136

 

AC

30 (31.6)

   
 

AA

8 (8.4)

   
  1. *p > 0.05 is consistent with the Hardy-Weinberg equilibrium; ** Sequence of reference NT_010194.16.