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Table 4 Results of the Survival Analysis in GIST

From: Cyclin H expression is increased in GIST with very-highrisk of malignancy

Non-Disease-specific 1-year 3-year 5-year    
Overall survival 91% 79% 71%    
  1-year DSS (%) 3-year DSS (%) 5-year DSS (%) 1-year DFS (%) 3-year DFS (%) 5-year DFS (%)
Whole cohort       
Survival 96 87 84 80 76 72
Risk of malignancy according to Fletcher et al. 2002 [1]  
Very low 100 100 100 100 100 100
Low 100 95 95 95 95 95
Intermediate 100 100 100 100 100 100
High 89 71 65 53 44 38
Non-high 100 98 98 98 98 98
Cyclin H
Positive 90 80 72 78 67 67
Negative 97 89 87 80 79 73
Other criteria
Prim-local 100 97 94 95 90 85
Prim-metastasis 72 33 33 -- -- --
Met: any time 84 56 46 27 19 8
R 0 resection 97 94 90 88 86 85
R 1/2 resection 83 40 40 33 25 25
  1. DSS = disease specific survival; DSF = disease free survival