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Table 3 P values regarding different parameters in GIST

From: Cyclin H expression is increased in GIST with very-highrisk of malignancy

Independent Variables

TRD

DSS

DFS

Met/Rec

Count

Tests:

χ2/Fisher Exact

Log-Rank

Log-Rank

χ2/Fisher Exact

(n)

Sex

0.180

0.226

0.647

0.626

95

Localization (stomach vs. small bowel)

0.671

0.618

0.433

0.611

87

Tumour size (≥ 5 cm vs. <5 cm)

0.005

0.008

<0.001

<0.001

92

Tumour size (≥ 10 cm vs. <10 cm)

<0.001

<0.001

<0.001

<0.001

92

Mitotic rate (≥ 5/50 HPF vs. <5/50 HPF)

0.001

0.001

<0.001

<0.001

90

Mitotic rate (≥ 10/50 HPF vs. <10/50 HPF)

<0.001

<0.001

<0.001

<0.001

90

Histomorphology (spindle vs. not)

0.103

0.099

0.217

0.187

92

Fletcher (high vs. non-high)

<0.001

<0.001

<0.001

<0.001

93

Joensuu (high vs. non-high)

<0.001

<0.001

<0.001

<0.001

89

Miettinen (high vs. non-high)

0.001

<0.001

<0.001

<0.001

86

Hornick (high vs. non-high)

<0.001

<0.001

<0.001

<0.001

90

Primary tumour state (unifocal vs. not)

<0.001

<0.001

<0.001

--

93

CD34 (pos vs. neg)

0.680

0.511

0.744

1.000

74

Aktin (pos vs. neg)

1.000

0.818

0.844

1.000

64

Desmin (pos vs. neg)

1.000

0.930

0.602

1.000

47

Cyclin H (pos vs. neg)

0.369

0.189

0.692

0.806

95

Fletcher (high vs. non-high)

<0.001

<0.001

<0.001

<0.001

93

Cyclin H (pos vs. neg, only high-risk)

0.435

0.038

0.552

1.000

39

Cyclin H (pos high risk vs rest)

0.004

<0.001

0.001

0.011

95

Joensuu (high vs. non-high)

<0.001

<0.001

<0.001

<0.001

89

Cyclin H (pos vs. neg, only high-risk)

0.281

0.009

0.330

0.730

40

Cyclin H (pos. high-risk vs. rest)

0.004

<0.001

<0.001

0.007

89

Miettinen (high vs. non-high)

0.001

<0.001

<0.001

<0.001

86

Cyclin H (pos vs. neg, only high-risk)

0.681

0.050

0.967

0.696

32

Cyclin H (pos. high-risk vs rest)

0.035

<0.001

0.012

0.053

86

Hornick (high vs. non-high)

<0.001

<0.001

<0.001

<0.001

90

Cyclin H (pos vs. neg, only high-risk)

0.306

0.020

0.502

1.000

36

Cyclin H (pos. high-risk vs. rest)

0.003

<0.001

0.001

0.007

90